Yes, Savannahs should receive routine kitten vaccinations just like domestic cats. The type and number of vaccinations is sometimes debatable, but it is generally accepted that they should have at least two initial vaccinations as a kitten (most veterinarians recommend three), with one being after they are 12 weeks old, and then a booster at a year of age and then every one to three years thereafter. Many breeders recommend killed virus vaccinations only because exotic cats have been known to have serious reactions to the modified live viruses. However, killed virus vaccinations have been associated with sarcomas at the injection site. Modified live viruses do not have this same concern so more breeders are beginning to use the modified live virus vaccinations. You may find your breeder will be very specific and require you to use only a certain type of vaccination, another breeder will allow you to choose your personal preference.